BRAF V600E Mutation in First-Line Metastatic Colorectal Cancer: An Analysis of Individual Patient Data From the ARCAD Database.
Romain CohenHeshan LiuJack FiskumRichard A AdamsBenoist ChibaudelTimothy S MaughanEric Van CutsemAlan P VenookJean-Yves DouillardVolker HeinemannCornelis Ja PuntAlfredo FalconeCarsten BokemeyerRichard S KaplanHeinz-Josef LenzMiriam KoopmanTakayuki YoshinoJohn ZalcbergAlex GrotheyAimery de GramontQian ShiThierry AndréPublished in: Journal of the National Cancer Institute (2022)
Our data suggest that the addition of anti-EGFR agents to chemotherapy is ineffective as first-line treatment for BRAFmt mCRC patients.
Keyphrases
- metastatic colorectal cancer
- end stage renal disease
- electronic health record
- newly diagnosed
- chronic kidney disease
- ejection fraction
- big data
- peritoneal dialysis
- epidermal growth factor receptor
- case report
- prognostic factors
- emergency department
- machine learning
- locally advanced
- artificial intelligence
- chemotherapy induced