Lycium barbarum polysaccharide inhibits ischemia-induced autophagy by promoting the biogenesis of neural stem cells-derived extracellular vesicles to enhance the delivery of miR-133a-3p.

Rong LiWenjie DuanTingle FengChenyang GuQiankun ZhangJun LongShiying HuangLu-Kui Chen

Published in: Chinese medicine (2023)

LBP activated AMPK/mTOR signaling pathway by increasing the enrichment and transfer of miR-133a-3p in NSC-EVs to inhibit stroke-induced autophagy activity.

Keyphrases

signaling pathway
neural stem cells
high glucose
diabetic rats
cell death
oxidative stress
endoplasmic reticulum stress
drug induced
atrial fibrillation
epithelial mesenchymal transition
induced apoptosis
blood brain barrier