A Multimodal Biomarker Predicts Dissemination of Bronchial Carcinoid.
Ellen M B P ReulingDwayne D NavesPim C KortmanMark A M BroeckaertPeter W PlaisierChris DickhoffJohannes M A DanielsTeodora RadonicPublished in: Cancers (2022)
Mitotic count, proliferation index, and OTP IHC were independent predictors of dissemination at follow-up. In addition to the widely used carcinoid classification, a comprehensive analysis of histopathological variables including Ki-67, OTP, and CD44 could assist in the determination of distant metastasis risks of bronchial carcinoids.