Late Onset Nephrogenic Systemic Fibrosis in a Patient with Stage 3 Chronic Kidney Disease: a Case Report.
Yu Jeong LimJisun BangYoungsun KoHyun-Min SeoWoon Yong JungJoo Hark YiSang-Woong HanMi-Yeon YuPublished in: Journal of Korean medical science (2020)
Nephrogenic systemic fibrosis (NSF) is a progressive systemic fibrosing disease that may occur after gadolinium contrast exposure. It can lead to severe complications and even death. NSF is highly prevalent among patients with advanced chronic kidney disease (CKD). In this report, however, we describe the case of a patient with NSF that occurred during early CKD. A 65-year-old man with stage 3a CKD was transferred to our hospital because of lower extremity edema. The medical history revealed that he was exposed to gadolinium 185 days earlier, and the result of his tibial skin biopsy was consistent with NSF. The patient underwent a combined therapy with ultraviolet-A1 phototherapy and methotrexate and steroid therapy for 6 months. The combined therapy stopped the systemic progression of NSF.
Keyphrases
- chronic kidney disease
- end stage renal disease
- late onset
- case report
- early onset
- healthcare
- multiple sclerosis
- contrast enhanced
- stem cells
- low dose
- interstitial lung disease
- risk factors
- mesenchymal stem cells
- ultrasound guided
- liver fibrosis
- systemic sclerosis
- peritoneal dialysis
- adverse drug
- idiopathic pulmonary fibrosis