Modeling colorectal cancer: A bio-resource of 50 patient-derived organoid lines.
Rebekah M EngelThierry JardéKaren OlivaGenevieve KerrWing Hei ChanSara HlavcaDavid NicklessStuart K ArcherRaymond YapPravin RanchodStephen BellAnn NiapChristine GeorgesAshley ChongSimon WilkinsTrevor C DaleAndrew J HollinsPaul J McMurrickHelen E AbudPublished in: Journal of gastroenterology and hepatology (2022)
Patient-derived colorectal cancer organoids recapitulate characteristics of the tissue from which they are derived and are a powerful tool for cancer research. Further research will determine their utility for predicting patient outcomes in a personalized cancer medicine setting.