Plasma cell-free DNA variant analysis compared with methylated DNA analysis in renal cell carcinoma.
Kathryn LasseterAmin H NassarLana HamiehJacob E BerchuckPier Vitale NuzzoKeegan KorthauerAtul B ShinagareBarbara OgorekRana McKayAaron R ThornerGwo-Shu Mary LeeDavid A BraunRupal S BhattMatthew FreedmanToni K ChoueiriDavid J KwiatkowskiPublished in: Genetics in medicine : official journal of the American College of Medical Genetics (2020)
cfMeDIP-seq is significantly more sensitive for mRCC detection than cfDNA variant analysis. However, cfDNA variant analysis may be useful for monitoring response to therapy.