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Risk factors associated with the occurrence of total knee arthroplasty in patients with knee osteoarthritis: a nested case-control study.

Jean-Pierre PelletierMarc DoraisPatrice PaiementJean-Pierre RaynauldJohanne Martel-Pelletier
Published in: Therapeutic advances in musculoskeletal disease (2022)
This study provides new information about gender differences in risk factors associated with the occurrence of TKA. Worsening of valgus alignment, cartilage volume loss in the lateral compartment, BMLs and older injuries are important risk factors in women, while medial compartment cartilage loss and meniscal extrusion are in men. The use of pain medication and IASI although associated was found not causal with TKA.
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