Circadian asthma airway responses are gated by REV-ERBα.
Hannah Jane DurringtonKarolina KrakowiakPeter MeijerNicola BegleyRobert MaidstoneLaurence GooseyJulie E GibbsJohn F BlaikleyLisa G GregoryClare M LloydAndrew S I LoudonDavid W RayPublished in: The European respiratory journal (2020)
These insights suggest the importance of considering the timing of drug administration in clinic trials and in clinical practice (chronotherapy).