Risk of gout among Taiwanese adults with ALDH-2 rs671 polymorphism according to BMI and alcohol intake.

Yu-Ruey LiuDisline Manli TantohChuan-Chao LinChih-Hsuan HsiaoYung Po Liaw

Published in: Arthritis research & therapy (2021)

Alcohol and abnormal BMI were associated with a higher risk of gout, whereas the rs671 GA+AA genotype was associated with a lower risk. Noteworthy, BMI and alcohol had a significant interaction on gout risk. Stratified analyses revealed that alcohol drinking especially among normal-weight individuals might elevate the risk of gout irrespective of the genotype.

Keyphrases

uric acid
body mass index
alcohol consumption
weight gain
metabolic syndrome
pet ct
weight loss