Multigene panels in prostate cancer risk assessment: a systematic review.

Julian LittleBrenda WilsonRon CarterKate WalkerPasqualina SantaguidaEva TomiakJoseph BeyeneMuhammad Usman AliParminder Raina

Published in: Genetics in medicine : official journal of the American College of Medical Genetics (2015)

The evidence on currently available SNP panels is insufficient to assess analytic validity, and at best the panels assessed would add a small and clinically unimportant improvement to factors such as age and family history in risk stratification (clinical validity). No evidence on the clinical utility of current panels is available.Genet Med 18 6, 535-544.

Keyphrases

prostate cancer
risk assessment
radical prostatectomy
genome wide
human health
gene expression