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Comparing efficacy and safety of upfront treatment strategies for anaplastic lymphoma kinase-positive non-small cell lung cancer: a network meta-analysis.

Marco FilettiPasquale LombardiRosa FalconeRaffaele GiustiDiana GiannarelliAntonella CarcagnìValeria AltamuraGiovanni ScambiaGennaro Daniele
Published in: Exploration of targeted anti-tumor therapy (2023)
Based on the network meta-analysis, alectinib and lorlatinib emerged as the most promising upfront treatment options. These treatments provide prolonged disease control while maintaining an acceptable safety profile.
Keyphrases
  • systematic review
  • meta analyses
  • diffuse large b cell lymphoma
  • protein kinase
  • tyrosine kinase
  • case control