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Early-onset diabetes mellitus as a presenting feature of Werner's syndrome in an Indian family.

Fieke W HoffChao XingVinaya SimhaAnil K AgarwalXunzhi ZhangLeena LekkalaMadhumati S VaishnavFrank VuitchAbhimanyu Garg
Published in: Molecular genetics & genomic medicine (2023)
Our report brings to attention the onset of DM during childhood or early adulthood in patients with Werner's syndrome who typically develop type 2 DM around the age of 30-40 years. Presence of consanguinity among parents, dysmorphic features, and malignancy should prompt consideration of diagnosis of Werner's syndrome.
Keyphrases
  • early onset
  • case report
  • late onset
  • machine learning
  • depressive symptoms
  • glycemic control
  • deep learning
  • young adults
  • weight loss
  • childhood cancer