Nutritional status in irritable bowel syndrome: A North American population-based study.
Isabel A HujoelPublished in: JGH open : an open access journal of gastroenterology and hepatology (2020)
The findings suggest that individuals with IBS should be screened for copper-zinc imbalance. Given zinc's role in the immune system, the "brain-gut" axis, and the gastrointestinal barrier, the identified copper-zinc imbalance may play a role in perpetuating the underlying pathophysiology of IBS. Further studies are needed to investigate this hypothesis and the potential role of therapeutic zinc supplementation.