Corticosteroid exposure prior to admission and predicting need for rescue therapy in acute severe ulcerative colitis.

Prolonged steroid use prior to ASUC admission is a significant predictor of need for rescue therapy. A generalised linear model incorporating steroid prior to admission, endoscopic Mayo score, and albumin was highly accurate at predicting failure of corticosteroid. Consideration should be given for commencement of rescue therapy prior to day three, especially in those with prolonged steroid prior to admission. This article is protected by copyright. All rights reserved.