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Autoreactive plasmablasts after B cell depletion with rituximab and relapses in ANCA-associated vasculitis.

Alvise BertiSophie HillionMaximilian Ferdinand KonigMarta Casal MouraAmber M HummelEva CarmonaTobias PeikertFernando C FervenzaCees G M KallenbergCarol A LangfordPeter A MerkelPaul A MonachPhilip SeoRobert F SpieraPaul BrunettaE William St ClairKristina M HarrisJohn H StoneGuido GrandiJacques-Olivier PersUlrich SpecksDivi Cornec
Published in: Arthritis & rheumatology (Hoboken, N.J.) (2022)
The composition of autoreactive B cell pool varies significantly following rituximab treatment in AAV, and early plasmablast enrichment within the autoreactive pool is associated with future relapses.
Keyphrases
  • diffuse large b cell lymphoma
  • chronic lymphocytic leukemia
  • hodgkin lymphoma
  • current status
  • gene therapy
  • combination therapy