The KDM6A-SPARCL1 axis blocks metastasis and regulates the tumour microenvironment of gastrointestinal stromal tumours by inhibiting the nuclear translocation of p65.
Chaoyong ShenLuyin HanBaike LiuGuixiang ZhangZhaolun CaiXiaonan YinYuan YinZhixin ChenBo ZhangPublished in: British journal of cancer (2022)
Our findings establish the critical role of the KDM6A-SPARCL1-p65 axis in restraining the malignancy of GIST.
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