Atlas of gut microbe-derived products from aromatic amino acids and risk of cardiovascular morbidity and mortality.
Ina NemetXinmin S LiArash HaghikiaLin LiJennifer WilcoxKymberleigh A RomanoJennifer A BuffaMarco WitkowskiIlja DemuthMaximilian KönigElisabeth Steinhagen-ThiessenFredrik BäckhedMichael A FischbachW H Wilson TangUlf LandmesserStanley L HazenPublished in: European heart journal (2023)
Key gut microbiota-generated metabolites derived from aromatic amino acids independently associated with incident adverse cardiovascular outcomes are identified, and thus will help focus future studies on gut-microbial metabolic outputs relevant to host cardiovascular health.