COvalent monolayer patterns in Microfluidics by PLasma etching Open Technology - COMPLOT.
Stan B J WillemsJaccoline ZegersAnton BunschotenR Martijn WagterveldFijs W B van LeeuwenAldrik H VeldersVittorio SaggiomoPublished in: The Analyst (2020)
Plasma microcontact patterning (PμCP) and replica molding were combined to make PDMS/glass microfluidic devices with β-cyclodextrin (β-CD) patterns attached covalently on the glass surface inside microchannels. The supramolecular reactivity, reusability and association constant of β-CD with Cy5-Ad2 was tested by analyzing signal-to-noise ratios of patterns vs. spacing with fluorescence microscopy.