TRIM25-mediated XRCC1 ubiquitination accelerates atherosclerosis by inducing macrophage M1 polarization and programmed death.

Hongxian WuWei GaoYuanji MaXin ZhongJuying QianDong HuangJunbo Ge

Published in: Inflammation research : official journal of the European Histamine Research Society ... [et al.] (2024)

-PARP1-RIPK3 axis in regulating macrophage death during atherosclerosis, and we highlight the potential therapeutic significance of macrophage reprogramming regulation in preventing the development of atherosclerosis.

Keyphrases

cardiovascular disease
adipose tissue
dna repair
type diabetes
oxidative stress