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A cleft lip and palate gene, Irf6, is involved in osteoblast differentiation of craniofacial bone.

Jake ThompsonFabian MendozaEthan TanJessica Wildgrube BertolArju S GaggarGoo JunClaudia BiguettiWalid D Fakhouri
Published in: Developmental dynamics : an official publication of the American Association of Anatomists (2019)
Altogether, these findings suggest an autonomous role of Irf6 in regulating bone differentiation and mineralization. Developmental Dynamics 248:221-232, 2019. © 2019 Wiley Periodicals, Inc.
Keyphrases
  • bone regeneration
  • bone mineral density
  • dendritic cells
  • soft tissue
  • bone loss
  • copy number
  • gene expression
  • immune response