Antimicrobial Coating: Tracheal Tube Application.
Xuemeng ChenXiaomei LingGaowang LiuJinfang XiaoPublished in: International journal of nanomedicine (2022)
Ventilator-associated pneumonia (VAP) is a common and serious nosocomial infection in mechanically ventilated patients, increasing mortality, prolonging the patient length of stay, and increasing costs. In recent years, extensive studies on ventilator-associated pneumonia have shown that tracheal intubation plays an essential role in the pathogenesis of VAP, with the primary mechanism being the rapid colonization of the tracheal intubation surface by microbiota. Antibiotics do not combat microbial airway colonization, and antimicrobial coating materials offer new ideas to solve this problem. This paper reviews the current research progress on the role of endotracheal tube (ET) biofilms in the pathogenesis of VAP and antimicrobial coating materials.
Keyphrases
- staphylococcus aureus
- end stage renal disease
- cardiac arrest
- ejection fraction
- intensive care unit
- newly diagnosed
- chronic kidney disease
- microbial community
- prognostic factors
- peritoneal dialysis
- type diabetes
- acute respiratory distress syndrome
- coronary artery disease
- risk factors
- multidrug resistant
- cystic fibrosis
- acinetobacter baumannii
- patient reported
- drug resistant
- mechanical ventilation