The metabolic phenotype of patients with primary aldosteronism: impact of subtype and sex - a multicenter-study of 3566 Caucasian and Asian subjects.
Ariadni SpyroglouLaura HandgriffLisa MüllerPaul SchwarzlmüllerMirko Parasiliti-CaprinoCarmina Teresa FussHana RemdeAnna HirschSamuel Matthew O'TooleMoe ThuzarLuigi PetramalaClaudio LetiziaElisa DeflorenneLaurence AmarRok VrckovnikTomaz KocjanCatherine D ZhangDingfeng LiSumitabh SinghTakuyuki KatabamiTakashi YonedaMasanori MurakamiNorio WadaNobuya InagakiMarcus QuinklerEzio GhigoMauro MaccarioMichael StowasserWilliam M DrakeFassnacht MartinIrina BancosMartin ReinckeMitsuhide NaruseFelix BeuschleinPublished in: European journal of endocrinology (2022)
Metabolic alterations appear more prominent in women with IHA. Although IHA patients have worse metabolic profiles, a correlation with cortisol autonomy is documented only in APAs, suggesting an uncoupling of cortisol action from metabolic traits in IHA patients.