Association of DIO2 and MCT10 Polymorphisms with Persistent Symptoms in LT4-Treated Patients in UK Biobank.

Christian Zinck JensenJonas Lynggaard IsaksenGustav AhlbergMorten Salling OlesenBirte NygaardChristina EllervikJørgen Kim Kanters

Published in: The Journal of clinical endocrinology and metabolism (2023)

rs225014, rs225015, rs12885300, and rs17606253 could not explain changed psychological well-being, cognitive function, or cardiovascular risk factors in LT4-treated patients. Our findings do not support a gene-treatment interaction between these SNPs and LT4 treatment.

Keyphrases

end stage renal disease
newly diagnosed
cardiovascular risk factors
ejection fraction
chronic kidney disease
prognostic factors
type diabetes
cardiovascular disease
dna methylation
patient reported outcomes
transcription factor
combination therapy
copy number
smoking cessation