Body composition is associated with tacrolimus pharmacokinetics in kidney transplant recipients.

M I FranckeW J VisserD SeversA M E de Mik-van EgmondD A HesselinkB C M De Winter

Published in: European journal of clinical pharmacology (2022)

The phase angle is the bio-impedance spectroscopic parameter that correlates best with tacrolimus pharmacokinetics. Incorporation of the phase angle in a popPK model can improve the prediction of an individual's tacrolimus dose requirement after transplantation.

Keyphrases

body composition
resistance training
bone mineral density
high resolution
molecular docking
computed tomography
magnetic resonance
magnetic resonance imaging
molecular dynamics simulations
contrast enhanced