Characterization of the MurT/GatD complex in Mycobacterium tuberculosis towards validating a novel anti-tubercular drug target.

Arundhati MaitraSyamasundari NukalaRachael DickmanLiam T MartinTulika MunshiAntima GuptaAdrian J ShepherdKristine B ArnvigAlethea B TaborNicholas H KeepSanjib Bhakta

Published in: JAC-antimicrobial resistance (2021)

Understanding the role of the enzyme complex in the context of PG metabolism and cell division, and the implications for antimicrobial resistance and host immune responses will facilitate the design of therapeutics that are targeted specifically to M. tuberculosis.

Keyphrases

antimicrobial resistance
mycobacterium tuberculosis
immune response
pulmonary tuberculosis
single cell
cell therapy
cancer therapy
adverse drug
emergency department
drug induced