Vitamin D3 enhances the response to cisplatin in bladder cancer through VDR and TAp73 signaling crosstalk.

Brittany L Bunch Yingyu MaKristopher AttwoodLauren AmableWei LuoCarl MorrisonKhurshid A GuruAnna WoloszynskaPamela A HershbergerDonald L TrumpCandace S Johnson

Published in: Cancer medicine (2019)

Our data suggest that VitD deficiency could be a biomarker for poor response to cisplatin, and pretreating with VitD can increase the apoptotic response to cisplatin through VDR and TAp73 signaling crosstalk.

Keyphrases

cell death
electronic health record
big data
machine learning
anti inflammatory
artificial intelligence