Azithromycin, a potent autophagy inhibitor for cancer therapy, perturbs cytoskeletal protein dynamics.
Naoharu TakanoMasaki HiramotoYumiko YamadaHiroko KokubaMayumi TokuhisaHirotsugu HinoKeisuke MiyazawaPublished in: British journal of cancer (2023)
As drug-repurposing, our results indicate that AZM is a potent autophagy inhibitor for cancer treatment, which acts by directly interacting with cytoskeletal proteins and perturbing their dynamics.