Decreased markers of bone turnover in children and adolescents with type 1 diabetes.

Jens Otto Broby Madsen Camilla Winther HerskinBo ZerahnNiklas Rye JørgensenBirthe Susanne OlsenFlemming PociotJesper Johannesen

Published in: Pediatric diabetes (2020)

Markers of bone formation and resorption were decreased in children and adolescents with T1D. CTX Z-score associated negatively with HbA1c adjusted for insulin treatment and endogenous insulin production indicating a potential association between CTX and insulin sensitivity. The long-term consequences of decreased BTM on BMD need further attention.

Keyphrases

type diabetes
bone mineral density
klebsiella pneumoniae
bone loss
escherichia coli
risk assessment
metabolic syndrome
soft tissue
adipose tissue
skeletal muscle
human health
insulin resistance