Particulate cartilage and platelet-rich plasma treatment for knee chondral defects in sheep.

Lourdes Alcaide-RuggieroVerónica Molina-HernándezJuan MorgazJ Andrés Fernández-SarmientoMaría M GranadosRocío Navarrete-CalvoJosé PérezSetefilla Quirós-CarmonaJosé M CarrilloRamón CugatJuan M Domínguez

Published in: Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA (2023)

The results suggest that macroscopic appearance, histological structure and chondrocyte repair were improved when using PACI + PRP treatment for chondral defects, producing an outcome similar to the surrounding healthy cartilage. PACI + PRP is a totally autologous, easy, and unexpensive treatment that can be performed in one-step procedure and is useful as a therapeutic option for knee chondral defects.

Keyphrases

platelet rich plasma
total knee arthroplasty
stem cells
knee osteoarthritis
bone marrow
mesenchymal stem cells
minimally invasive
combination therapy
smoking cessation
anterior cruciate ligament reconstruction