Constructing High-Fidelity Phenotype Knowledge Graphs for Infectious Diseases With a Fine-Grained Semantic Information Model: Development and Usability Study.

PhenoSSU is an effective information model for the precise representation of phenotype knowledge for clinical guidelines, and machine learning can be used to improve the efficiency of constructing PhenoSSU-based knowledge graphs. Our work will potentially shift the focus of medical knowledge engineering from a coarse-grained level to a more fine-grained level.