Simvastatin ameliorates synaptic plasticity impairment in chronic mild stress-induced depressed mice by modulating hippocampal NMDA receptor.

Xu-Ben YuKai-Long ZhongChuang ChenJing FuFang ChenHong-Min ZhouXiu-Hua ZhangKwonseop KimJing-Ye Pan

Published in: Psychopharmacology (2023)

These findings suggest that simvastatin can improve the dysfunction of NMDAR and ameliorate hippocampal synaptic plasticity impairment in depressed mice.

Keyphrases

stress induced
high fat diet induced
type diabetes
wild type
temporal lobe epilepsy
insulin resistance
brain injury
subarachnoid hemorrhage
drug induced