Levosimendan combined with epinephrine improves rescue outcomes in a rat model of lipid-based resuscitation from bupivacaine-induced cardiac arrest.

Fubei NanXixi CaiYingchao YeXuzhong XuZhengqian LiMin LiLimei Chen

Published in: BMC anesthesiology (2017)

Levosimendan combined with epinephrine may be superior to either drug alone for lipid-based resuscitation in a rat model of bupivacaine-induced cardiac arrest. The drug combination was associated with a higher survival rate as well as decreased epinephrine consumption and lung damage.

Keyphrases

cardiac arrest
cardiopulmonary resuscitation
high glucose
drug induced
diabetic rats
cardiac surgery
pain management
oxidative stress
postoperative pain
emergency department
metabolic syndrome
adipose tissue
adverse drug
acute kidney injury
insulin resistance
septic shock