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Mini review shows that a testicular volume of 3 mL was the most reliable clinical sign of pubertal onset in males.

Kjersti Kvernebo SunnergrenJovanna DahlgrenCarina Ankarberg-Lindgren
Published in: Acta paediatrica (Oslo, Norway : 1992) (2023)
A substantial amount of evidence supports testicular volume of 3 mL as the most reliable clinical sign of male pubertal onset.
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