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Virulence characterization and comparative genomics of Listeria monocytogenes sequence type 155 strains.

Eva WagnerAndreas ZaiserRebekka LeitnerNarciso M QuijadaNadja PracserAriane PietzkaWerner RuppitschStephan Schmitz-EsserMartin WagnerKathrin Rychli
Published in: BMC genomics (2020)
This study contributes to an enhanced understanding of L. monocytogenes ST155 strains, being equally distributed among isolates from humans, food, and food processing environments. The conservation of the present genetic traits and the absence of unique inherent genetic features makes these types of STs especially interesting since they are apparently equally adapted to the conditions in food processing environments, as well as in food as to the human host environment. However, a ST155-specific mutation resulting in a longer PrfA variant impaired the virulence potential of several ST155 strains.
Keyphrases
  • escherichia coli
  • human health
  • genome wide
  • pseudomonas aeruginosa
  • staphylococcus aureus
  • biofilm formation
  • endothelial cells
  • risk assessment
  • antimicrobial resistance
  • dna methylation