Development and validation of a risk prediction model for linezolid-induced thrombocytopenia in elderly patients.
Yan QinZhe ChenShuai GaoYun ShenYanrong YePublished in: European journal of hospital pharmacy : science and practice (2022)
These findings indicate that duration of linezolid therapy, age, eGFR, ICU admittance, baseline platelet counts, concomitant piperacillin-tazobactam were significantly associated with LI-TP in elderly patients. A risk prediction model based on these risk factors showed a good discriminative performance and may be useful for clinicians to identify patients at high risk of developing LI-TP.
Keyphrases
- risk factors
- ion batteries
- methicillin resistant staphylococcus aureus
- small cell lung cancer
- high glucose
- intensive care unit
- diabetic rats
- epidermal growth factor receptor
- tyrosine kinase
- palliative care
- solid state
- stem cells
- gram negative
- endothelial cells
- staphylococcus aureus
- mesenchymal stem cells
- multidrug resistant
- extracorporeal membrane oxygenation