Cytology of micropapillary mucinous carcinoma: A case report of a clinically and genetically distinct breast carcinoma variant.
Immanuel PradeepJitendra Singh NigamGunvanti RathodTushar Mohanlal ParmeshwarPublished in: Diagnostic cytopathology (2023)
Micropapillary mucinous carcinoma (MPMC) is an uncommon histopathological variant of breast cancer accounting for approximately one-fifth of all mucinous breast carcinomas. In contrast to pure mucinous carcinoma, MPMC tends to affect younger women and is associated with decreased progression-free survival, higher nuclear grade, lymphovascular invasion, lymph node metastasis, and positive HER2 status. Typically MPMC histology shows micropapillary architecture with "hobnailing" of cells and reverse polarity. Very few publications document the cytomorphological findings of MPMC. We report a case of MPMC that was suspected in fine needle aspiration cytology (FNAC) and confirmed at histopathology.
Keyphrases
- fine needle aspiration
- lymph node metastasis
- low grade
- high grade
- ultrasound guided
- free survival
- squamous cell carcinoma
- papillary thyroid
- induced apoptosis
- polycystic ovary syndrome
- cell cycle arrest
- type diabetes
- magnetic resonance imaging
- cell migration
- pregnancy outcomes
- endoplasmic reticulum stress
- computed tomography
- insulin resistance
- pregnant women
- skeletal muscle
- cell death