TGIF1 Knockdown Inhibits the Proliferation and Invasion of Gastric Cancer via AKT Signaling Pathway.

Jing ZhangFeiyan ZhangJiye FanBin Feng

Published in: Cancer management and research (2021)

TGIF1 knockdown inhibited the proliferation, migration, and invasion and promoted apoptosis of gastric cancer cells via the AKT signaling pathway, suggesting that TGIF1 is considered a potential inhibitor in gastric cancer.

Keyphrases

signaling pathway
pi k akt
cell cycle arrest
induced apoptosis
epithelial mesenchymal transition
oxidative stress
endoplasmic reticulum stress
cell death