Optimizing relapse prevention and changing habits (REACH+) in anorexia nervosa.
Joanna E SteinglassEvelyn AttiaDeborah R GlasoferYuanjia WangJulia RuggieroB Timothy WalshJ Graham ThomasPublished in: The International journal of eating disorders (2022)
Participants will be 60 adults with AN who have achieved weight restoration in an inpatient setting. Treatment will consist of 6 months of outpatient telehealth sessions. REACH+ consists of behavior, cognitive, and motivation components, as well as food monitoring and a skill consolidation phase. A specialized online platform extends therapy between sessions. Participants will be randomly assigned to different versions of each component in a fractional factorial design. Outcomes will focus on maintenance of remission, measured by rate of weight loss and end-of-trial status. Interventions that contribute to remission will be included in an optimized treatment package, suitable for a large-scale clinical trial of relapse prevention in AN.
Keyphrases
- clinical trial
- weight loss
- anorexia nervosa
- physical activity
- palliative care
- study protocol
- phase ii
- healthcare
- mental health
- type diabetes
- phase iii
- body mass index
- metabolic syndrome
- open label
- combination therapy
- roux en y gastric bypass
- mesenchymal stem cells
- bone marrow
- health information
- skeletal muscle
- glycemic control
- replacement therapy
- body weight
- obese patients