Tuberculosis (TB) treatment challenges in TB-diabetes comorbid patients: a systematic review and meta-analysis.

Mahnoor KhattakAnees Ur RehmanTuba MuqaddasRabia HussainMuhammad Fawad RasoolZikria SaleemMesfer Safar AlmalkiSamar Adel AlturkistaniShuruq Zuhair FirashOseid Mohammed AlzahraniAmmar Abdulraheem BahauddinSafa Almarzooky AbuhussainMuath Fahmi NajjarHossameldeen Mahmoud Ali ElsabaaAbdul Haseeb

Published in: Annals of medicine (2024)

A negative impact of DM was found on recurrence and extended treatment duration in TB patients treated with DOTS therapy. DM type 2 is responsible for the TB treatment prolongation and TB recurrence rates. By implementing effective management strategies and advancing research, the challenges can be mitigated, arising due to the complex interaction between DM and TB.

Keyphrases

mycobacterium tuberculosis
type diabetes
cardiovascular disease
end stage renal disease
chronic kidney disease
newly diagnosed
stem cells
glycemic control
metabolic syndrome
emergency department
adipose tissue
prognostic factors
skeletal muscle
cell therapy
weight loss