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Thiazides Attenuate Insulin Secretion Through Inhibition of Mitochondrial Carbonic Anhydrase 5b in β-islet Cells in Mice.

Patrycja KucharczykGiuseppe AlbanoChristine DeislTin Manh HoMatteo BargagliManuel AndereggStephan WueestDaniel KonradDaniel G Fuster
Published in: Journal of the American Society of Nephrology : JASN (2023)
Thiazides attenuate insulin secretion via inhibition of the mitochondrial CA5b isoform in β-cells of mice.
Keyphrases
  • induced apoptosis
  • oxidative stress
  • cell cycle arrest
  • high fat diet induced
  • endoplasmic reticulum stress
  • signaling pathway
  • cell death
  • cell proliferation