The Role of Sulfhydryl (Thiols) Groups in Oral and Periodontal Diseases.
Sabetim CerkeziMarija NakovaIcko GorgoskiKenan FeratiArberesha Bexheti-FeratiAndrea PalermoAlessio Danilo InchingoloLaura FerranteAngelo Michele InchingoloInchingolo FrancescoGianna DipalmaPublished in: Biomedicines (2024)
The results of this study showed significantly decreased levels of sulfhydryl (thiols) groups in gingival tissue from patients with gingivitis and periodontitis, compared with healthy people (control group). These results confirm the role of sulfhydryl (thiols) groups in defense against free radicals. They share a significant role in detoxification, signal transduction, apoptosis, and various other functions at the molecular level.