Advanced ankylosing spondylitis: a multisite, multimodality densitometric analysis for investigation of bone loss in the axial and appendicular skeleton.
Stavroula J TheodorouDaphne J TheodorouYousuke KakitsubataIoannis GelalisNiki TsifetakiPublished in: Revista da Associacao Medica Brasileira (1992) (2021)
Low bone mineral density is prevalent in advanced ankylosing spondylitis patients, predominating in the spine. Bone mineral density measurements have systematic differences when compared to each other. Knowledge of these offsets is useful for improved diagnosis of regional bone loss that allows for targeted treatment of osteoporosis. Three-dimensional quantitative computed tomography is more suitable for evaluating spinal osteoporosis in advanced ankylosing spondylitis than dual-energy X-ray absorptiometry, which rather underestimates bone loss.
Keyphrases
- ankylosing spondylitis
- bone mineral density
- bone loss
- dual energy
- postmenopausal women
- computed tomography
- body composition
- rheumatoid arthritis
- disease activity
- end stage renal disease
- image quality
- newly diagnosed
- positron emission tomography
- chronic kidney disease
- healthcare
- spinal cord
- contrast enhanced
- high resolution
- magnetic resonance imaging
- systemic lupus erythematosus
- spinal cord injury
- drug delivery
- cancer therapy
- mass spectrometry
- electron microscopy