Update on cerebrovascular manifestations of COVID-19.
Reza NaeimiMaryam Ghasemi-KasmanPublished in: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology (2020)
The novel member of coronaviruses family, severe acute respiratory coronavirus-2 (SARS-CoV-2), with high structural homology to SARS-CoV and Middle East respiratory syndrome-related coronavirus (MERS) has spread rapidly with about 20 million cases infection and over 700,000 deaths. SARS-CoV-2 has been emerged as a worldwide disaster due to non-specific few respiratory and gastrointestinal manifestations at the onset of disease as well as long incubation period. Surprisingly, not only respiratory failure but also the underlying coagulation disorder and neurovascular involvement worsen the clinical outcome of infected patients. In this review article, we describe the probable mechanisms of SARS-CoV-2 infection and stroke occurrence. We will also discuss the cerebrovascular events following SARS-CoV-2 infection, the recommended therapies, and future prospects to better manage these patients in coronavirus disease 2019 (COVID-19) outbreak.
Keyphrases
- sars cov
- respiratory syndrome coronavirus
- coronavirus disease
- respiratory failure
- end stage renal disease
- newly diagnosed
- current status
- ejection fraction
- extracorporeal membrane oxygenation
- mechanical ventilation
- atrial fibrillation
- respiratory tract
- prognostic factors
- peritoneal dialysis
- intensive care unit
- patient reported outcomes