Association of Self-reported Systemic Reactions Following SARS-CoV-2 Vaccination With Immunological Response in the Danish National Cohort Study of Effectiveness and Safety of SARS-CoV-2 Vaccines (ENFORCE).
Wendy P BannisterDorthe RabenPalle Valentiner-BranthMartin TolstrupLykke LarsenBritta TarpMette Brouw IversenOle Schmeltz SøgaardSisse Rye OstrowskiNina Breinholt StærkeMarie Louise JakobsenSusan Olaf LindvigMaria Ruwald JuhlIsik Somuncu JohansenAhmed B MustafaLars ØstergaardFredrikke Dam LarsenLene Surland KnudsenVibeke KlastrupLothar WieseThomas Lars BenfieldKristine Toft PetersenKasper K IversenHenrik NielsenJoanne ReekieJens Dilling Lundgrennull nullPublished in: Open forum infectious diseases (2023)
An association was found between more severe adverse reactions and stronger antibody response after the second vaccination but not the first, likely attributed to higher levels of preexisting immunity gained from response to first vaccination. Regardless of side effects, most people experienced an effective immune response following vaccination.