Dopaminergic signaling and behavioral alterations by Comt-Dtnbp1 genetic interaction and their clinical relevance.

Francesca ManagòDiego ScheggiaMaria PontilloMaddalena MereuRosa MastrogiacomoGayatri UdayanPaola ValentiniMaria Cristina TataDaniel R WeinbergerCynthia S WeickertPier Paolo PompaMaria A De LucaStefano VicariFrancesco Papaleo

Published in: British journal of pharmacology (2023)

These findings illustrate a predicted epistatic interaction of two dopamine-related genes and their functional effects, supporting the need to address genetic interaction mechanisms at the base of complex behavioral traits.

Keyphrases

genome wide
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