Aging in psoriasis vulgaris: female patients are epigenetically older than healthy controls.
Pavel BorskyMarcela ChmelarovaZdenek FialaKvetoslava HamakovaVladimir PalickaJan KrejsekCtirad AndrysJan KremlacekVit RehacekMartin BeranekAndrea MalkovaTereza SvadlakovaDrahomira HolmannovaLenka BorskaPublished in: Immunity & ageing : I & A (2021)
The findings suggest a possible presence of pathophysiological processes that occur only in female psoriatic patients. These processes make psoriatic females biologically older and might lead to an increased risk of comorbidity occurrence. This study also supports the idea that autoimmune diseases cause accelerated aging, which should be further explored in the future.