The negative influence of baseline cell-free DNA on long-term survival in DLBCL depends on frontline treatment intensity.
Fabienne DesmotsDelphine RossilleMikael RousselCéline PangaultLaetitia LouarnMylène De Saint JoreSteven Le GouillKrimo BouabdallahVincent DelwailRemy GressinJérôme CornillonGandhi Laurent DamajHervé MaisonneuveDiane DamotteFrançoise Kraeber-BodéréThierry LamyMarie-Cécile ParrensNoel MilpiedThierry FestPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
In this randomized clinical trial, intensive regimens mitigated the negative influence of high cfDNA levels in de novo DLBCL, relative to R-CHOP.