Non-coding RNAs underlie genetic predisposition to breast cancer.

Mahdi Moradi MarjanehJonathan BeesleyTracy A O'MaraPamela MukhopadhyayLambros T KoufariotisStephen KazakoffNehal HusseinLaura FachalNenad BartonicekKristine M HillmanSusanne KaufmannHaran SivakumaranChanel E SmartAmy E McCart ReedKaltin FergusonJodi M SaunusSunil R LakhaniDaniel R BarnesAntonis C AntoniouMarcel E DingerNicola WaddellDouglas F EastonAlison M DunningGeorgia Chenevix-TrenchStacey L EdwardsJuliet D French

Published in: Genome biology (2020)

We have compiled the largest catalog of breast cancer-associated mencRNAs to date and provide evidence that modulation of mencRNAs by GWAS variants may provide an alternative mechanism underlying complex traits.

Keyphrases

genome wide
copy number
dna methylation
gene expression
young adults