Potential of peptide-engineered exosomes with overexpressed miR-92b-3p in anti-angiogenic therapy of ovarian cancer.
Jiaying WangConghui WangYang LiMingyue LiTingjia ZhuZhangjin ShenHui WangWeiguo LvXinyu WangXiaodong ChengXing XiePublished in: Clinical and translational medicine (2022)
Our findings demonstrate the effect and mechanism of exosomal miR-92b-3p from ovarian cancer cells on tumor-associated angiogenesis and the potential of artificially generated exosomes with overexpressed miR-92b-3p to be used as anti-angiogenic agent, which may provide a new approach for anti-angiogenic therapy of ovarian cancer.