An In Vitro Model of Diabetic Retinal Vascular Endothelial Dysfunction and Neuroretinal Degeneration.

Qiyun Wang Xinyuan ZhangKaiyue WangLing Zhu Bingjie Qiu Xiaosi ChenXiao LinYao Nie

Published in: Journal of diabetes research (2021)

We have optimized glucose concentrations to model diabetic retinal endothelial (25-50 mM) or neuronal (50-100 mM) dysfunction in vitro, which have a wide range of downstream applications.

Keyphrases

optical coherence tomography
diabetic retinopathy
type diabetes
wound healing
endothelial cells
oxidative stress
blood glucose
adipose tissue
blood pressure
blood brain barrier
brain injury
glycemic control